The CDC’s Antibiotic Resistance Threats in the US states that more than 2.8 million per year of antibiotic-resistant infections occur in the U.S., leading to more than 35,000 deaths per year In addition, blood cultures require large blood volumes (10-60 mL), with at least two vials.
When performed daily in hospitals, this leads to Hospital-Acquired Anemia (HAA) in 74% of patients and 100% of infants in the NICU.
Both blood and urine cultures also require more than 72 hours for results as culture flasks can be incubated for up to 5 days depending on pathogens.
Patients are prescribed antibiotics and antivirals preemptively well before the culture results, leading to even more overuse and resistance.
The 4th issue for BPC are laboratory costs, which are out of reach for disaster areas, refugee camps, MD offices, and areas without health care infrastructure.
The goal is to increase reliability, accuracy, speed, portability, and access to both urine and blood cultures.
In the case of blood, the added goal is to decrease Hospital-Acquired Anemia, its costs, by decreasing blood volumes.
Our new hand-held, portable blood diagnostic device called InnovaBug™ can detect in minutes, pathogen load in from 0.03 – 0.3 mL fluid drops. It uses a fluorescent colorimetric reaction, a rapid, compact technology parallel to the technology in well-established blood plasma glucose meters.
Because detection can happen in minutes, and can be used at the bedside, camps and remote areas, or MD offices, border crossings, etc., it reviews a pathogen load present in the blood or urine at the time of collection instead of growing a new load due pathogen contamination when time elapses with day-long blood cultures. InnovaBug avoids detecting contamination that grows, multiplies and loads blood and urine later.
InnovaBug can help:
- Eliminate quickly and cheaply truly negative urine and blood samples with just a few drops to detect the actual presence of a pathogen load before contaminants have a chance to grow.
Since 80% of pathogen culture come back negative, InnovaBug reduces unnecessary cultures, and associated costs by 80%.
- Detects pathogen loads already grown and present in blood and urine at the time of collection in minutes, without the risk of pathogen loads from growing contamination seeded during collection. InnovaBug can identify direct pathogen loaded blood and urine samples that need to be cultured for identification. This constitutes about a 1/5th in average of all samples collected.